منابع مشابه
Desferrioxamine chelatable body iron.
Further experience with the differential ferrioxamine test (Fielding, 1965) for the measurement of body-iron chelation has led to modifications which include (1) an improved standard for the estimation of ferrioxamine, (2) simplified preparation of the test dose, (3) restriction of fluid during the test and (4) simplified methods of calculation. The principle of the test remains the same: an in...
متن کاملchelatable body iron
SYNOPSIs The differential ferrioxamine test is a simple method for the measurement of chelation of body iron by desferrioxamine. A single six-hour specimen of urine is obtained after intravenous Desferal, accompanied by 59Fe-ferrioxamine. Two values are measured: Fd, the excretion of ferrioxamine derived from body iron by chelation, and Fex, the proportion of ferrioxamine excreted from a known ...
متن کاملDesferrioxamine-chelatable iron, a component of serum non-transferrin-bound iron, used for assessing chelation therapy.
This study introduces a method for monitoring a component of serum non-transferrin-bound iron (NTBI), termed "desferrioxamine-chelatable iron" (DCI). It is measured with the probe fluorescein-desferrioxamine (Fl-DFO), whose fluorescence is stoichiometrically quenched by iron. DCI was found in the serum of most patients with thalassemia major (21 of 27 tested, range 1.5-8.6 microM), but only in ...
متن کاملRelationship of hepatic iron concentration to histochemical grading and to total chelatable body iron in conditions associated with iron overload.
A simple method based on atomic absorption spectrophotometry and using protein concentration as the reference standard was used for measuring the total tissue iron concentration in needle liver biopsy specimens from 47 patients with varying levels of body iron stores. The values obtained showed a close correlation over a wide range with measurements of total chelatable body iron stores. A compa...
متن کاملTransferrin iron, chelatable iron and ferritin in idiopathic haemochromatosis.
In I Z patients with idiopathic liaciiiocliroiiiatosis aiid varying dcgrces of iroii ovcrload the scru~ii fcrritin coiicctitratioii was rclatcd to the aiiiouiit of iron mobilizcd by vciicsectioit. Tlicrc was 110 corrclation Lctwceii iron loadaiidcliclatablc iron. In 35 patients with normal iron storcs following vciic~cctioii therapy, both transfcrrin iron and cliclatablc iron was pathologically...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1967
ISSN: 0021-9746
DOI: 10.1136/jcp.20.4.668